LET Gel Topical Anesthetic

Carie Boyd Pharmaceuticals LET Gel is a topical, non-sterile, triple anesthetic gel that helps to effectively reduce pain during the suturing of wounds. Its formulation provides rapid and effective anesthetic to tissues, helping reduce the patient’s discomfort. Skin lacerations are a common cause of trips to the emergency department, accounting for over 8% of all visits. LET gel is a preferred anesthetic applied to open wounds prior to suturing.

• Lidocaine 4% – Lidocaine blocks sodium channels which, when applied to skin, prevents local neurons from signaling the brain, blocking the pain response. Onset of numbing is within 4 minutes.
• Epinephrine 0.18% – Epinephrine works as a vasoconstrictor in the superficial tissue bed to assist in control of superficial bleeding and helps to slow systemic absorption of the active ingredients, prolonging the maintenance of an active tissue concentration.
• Tetracaine 0.5% – Tetracaine is a longer acting anesthetic that functions by altering the function of ryanodine receptors that control the distribution of intracellular calcium, blocking the pain response.

We offer LET topical gel in 3mL unit-dose syringes, to hospital emergency departments, urgent care centers, pediatrician offices, and other qualified health care providers. Room temperature storage means providers can have LET gel on hand to use as needed.